Beschreibung
Resveratrol as a phyto-estrogenic polyphenolic compound extracted from red grapes, has a calorie restriction effect on colorectal cancer cells. It stimulates the metabolic re-programming of cells from the anaerobic glycolysis into oxidative respiration. So that it is called to be a glucose deprivation mimic drug with a chemo- preventive and chemo- therapeutic effects. The calorie restriction effect of resveratrol is the deriving force for the enhanced cytotoxicity and apoptosis and the reduced angiogeneis of colorectal cancer cells.
Autorenportrait
Mariam A. Fouad Hafez, PhD Cancer Biology (Pharmacology and Experimental Oncology), Lecturer in Pharmacology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Egypt.
