Adenoviruses:Model and Vectors in Virus Host Interactions

InhaltsangabePart 1: Virion and structure.-Molecular evolution of adenoviruses.-Novel partner proteins of adenovirus penton.-Structural studies on adenoviruses.-Part 2: Viral replication.-The multifunctional role of E1A in the transcriptional regulation of CREB/CBP-dependent target genes.-Mechanisms of adenovirus DNA replication.-Regulation of adenovirus packaging.-Adenovirus DNA replication: protein priming, jumping back and the role of the DNA binding protein DBP.-The structure and function of the major late promoter.-Part 3:Host-cell interactions.-Remodeling of the host-cell RNA splicing machinery during an adenovirus infection.-Regulation of mRNA production by the adenoviral E1B 55 kDa and E4 ORF6 proteins.-Adenovirus interaction with its cellular receptor CAR.-Transactivation of the human cdc2 promoter by adenovirus E1A.-Models and vectors in virus-host interactions.-Abortive infection of hamster cells by adenovirus type 12.-Subject index